Arbetsbeskrivning

Lund University was founded in 1666 and is repeatedly ranked among the world’s top universities. The University has around 46 000 students and 8 500 staff based in Lund, Helsingborg and Malmö. We are united in our efforts to understand, explain and improve our world and the human condition.

Lund University welcomes applicants with diverse backgrounds and experiences. We regard equality, equal opportunities and diversity as a strength and an asset.

Description of workplace

The research is conducted at the Biomedical Centre (BMC) in Lund, near Skåne University Hospital under the leadership of Associate professor Sandra Lindstedt. The focus lies on clinically oriented research concerning lung transplantation related research, post-transplant complications and lung regeneration.

We offer

Lund University is a governmental authority, which means you get special benefits, generous holidays, and a favorable occupational pension. Read more on the university's website about being employed at Lund University, Work at Lund University

We are seeking a driven and highly motivated Associate researcher with the ability to work independently and further develop ongoing research projects. The position is full-time. The suggested start date is January 1, 2027, or as agreed upon.

Work description

The duties at the research unit primarily consist of laboratory-based research, with a particular focus on cell culture, cell isolation, and gene therapy.

The successful candidate will primarily work on a research project investigating the reactivation of developmental signaling pathways in lung disease, with a particular focus on lung tissue repair and regeneration. The research will employ a combination of in vitro, ex vivo, and in vivo approaches. The position has a strong translational focus, bridging experimental/preclinical research and clinical medicine, primarily within the fields of thoracic surgery and pulmonary medicine.

The main responsibilities include:

• Independently designing, planning, and conducting research within the project, as well as collecting, analyzing, interpreting, and managing data generated throughout the project.
• The project involves advanced CRISPR/Cas9 genome editing, including tissue processing, protocol development and optimization, troubleshooting, and subsequent analysis and quantification.
• The work will also involve the isolation of cells from tissue and the characterization of both primary and commercially available cells, including analyses of proliferation, migration, immunocytochemistry (ICC), and related cellular functions.
• The position also includes responsibility for preparing high-quality scientific manuscripts for publication in international peer-reviewed journals.
• The majority of the work will be conducted independently, while also involving close collaboration with both internal and external members of the research team and other collaborators.
• In addition, the position includes mentorship and supervision of postdoctoral researchers, PhD students, and Master's students.

Basis for assessment

This is a merit-based position primarily focused on research. The position is intended as an initial step in the academic career, and the selection will be based primarily on scientific merit and potential as a researcher.

For postdoctoral appointments, the following shall form the basis for assessment:

• Proven ability to develop and conduct high-quality research
• Teaching and pedagogical ability

Additional qualifications will be assessed based on the following requirements for the position:

• PhD degree (or equivalent) in biochemistry, bioengineering, or cell and molecular biology.
• Technical proficiency and scientific creativity in one or more of the following areas: lungtransplantation, large animal models, CRISPR and / or cell modification.
• Background in translational work, lung transplant and large animal models.
• Experience with standard cellular and molecular biology techniques, including Western blotting, ELISA, mass spectrometry, qPCR, immunohistochemistry, and HPLC.
• Experience in the isolation, culture, and differentiation of primary cells.
• Experience with CRISPR/Cas9 genome editing of primary cells, including mesenchymal cells.

The research project is interdisciplinary, therefore candidates with a broad competence profile spanning theses different areas are of special interest.

Meritorious qualifications:

• Ability to run and coordinate interdisciplinary collaborations.
• Good written and verbal communication skills.
• Ability to carry out independent and high-quality research as documented through peer-reviewed publications.
• Documented Experience in mentoring and/or supervision.
• Good knowledge of clinical and translational lung transplantation.
• Developed gen modified cells for large animal models in lung transplantation.
• Hands-on experience of handling samples from patients and large animals.
• We look for a candidate that is highly motivated, positive and independent.

Eligibility

Appointment to a post-doctoral position requires that the applicant has a PhD, or an international degree deemed equivalent to a PhD, within the subject of the position. This eligibility requirement needs to be met no later than the time when the employment decision is made. We will mainly consider candidates who have completed their PhD degree no more than three (3) years before the last date for applications. Under special circumstances, the doctoral degree can have been completed earlier. These circumstances refer to leave due to illness, parental leave, clinical work, positions of trust within trade union organizations or other similar circumstances.

Terms of employment

This is a full-time employment limited to 2 years. Preliminary start is the 1st of January 2027, or according to agreement. The period of employment is determined in accordance with the agreement “Avtal om tidsbegränsad anställning som postdoktor”.

How to apply

The position is sought via the university's recruitment system.