Arbetsbeskrivning

Circio is a preclinical-stage biotechnology company developing a novel proprietary circular RNA expression platform for enhanced gene and cell therapies. This circular RNA platform enables high and durable expression of therapeutic proteins, with the potential to impact multiple therapeutic modalities across a broad range of disease areas. Circio is currently focused on unlocking the full potential of this platform in the field of T-cell therapies for cancer and autoimmune diseases.

For more information about the company, please visit: http://www.circio.com

Postdoctoral Immunologist – T-cell Biology / Cell Therapy

Location: Flemingsberg Science Park, Stockholm, Sweden

Circio is currently seeking an experienced Postdoctoral Immunologist with a strong background in T-cell biology. Hands-on experience with both mouse and human experimental systems, supported by relevant peer-reviewed publications, is highly desirable. The successful candidate will join Circio’s expanding R&D department, located at Flemingsberg Science Park in Stockholm, Sweden, and will serve as one of the scientific leaders in the development of Circio’s technology platform and pipeline of drug candidates in T-cell and CAR-T cell therapies.

Responsibilities

· Develop Circio’s in-house capabilities for assessing the performance of circular RNA-encoding vectors in T cells, as well as other immune cell subsets, both in vitro and in vivo

· Establish and support a network of CRO partners to further improve and accelerate the analysis of Circio’s lead drug candidates in the fields of autoimmunity and onco-immunology

· Contribute to drug-candidate conceptualization, design, selection, and prioritization

· Supervise technical assistants and junior scientists with the aim of building a strong immunology division within Circio

· Work closely with management and the broader R&D team to drive the company’s scientific objectives and priorities

Qualifications

· PhD and postdoctoral experience in immunology within academic and/or industrial settings are required

· Proven proficiency in planning and executing a wide range of immunological assays, including flow cytometry (FACS), primary human T-cell isolation, cell culture, and phenotypic/functional characterization

· Experience with molecular biology, protein chemistry, microscopy, and immunohistochemistry is considered an advantage

· Ability to independently process and analyze experimental data, and to present findings, conclusions, and future plans to diverse audiences both within and outside the company

What We Offer

Circio offers a varied and exciting work environment within an innovative and dynamic biotech company. You will have the opportunity to develop professionally through challenging tasks in a growing organization, while contributing to the development of novel treatments for a range of serious diseases.

Application

Interested candidates should send their CV and cover letter in English to [email protected] no later than May 15.

For additional information, please contact Ola Melin or Victor Levitsky via email at:

[email protected], [email protected]