Arbetsbeskrivning

Gnothis AB is seeking for a hands-on engineer who enjoys building experimental systems in a laboratory environment. The role combines microfluidics integration, instrument prototyping, and Python-based automation. This is a permanent position based at our HQ, located at the campus of Stockholm University (Stockholm, Sweden).

Gnothis, founded in 2015 and supported by highly innovative industrial professionals and technology developers, is on a mission to develop a new frontier for single molecule DNA sequencing; to break the mold on how sequencing is used as a clinical tool for the diagnosis of complex diseases. Gnothis technology integrates a wide range of cutting-edge sciences ranging from nanotechnology, photophysics, optics, surface chemistry, biochemistry and computational science.

Since we have taken significant steps forward and now need to solve the remaining crucial challenges before commercialization; for the right person this is a unique opportunity to become a valuable member, to use your “think-outside-the box” mentality with aim to develop a new world-class technology platform!

Our instrumentation, software and analysis team currently consists of four engineers and we are now expanding the team as we scale development of the system. The work is primarily on-site and very practical, involving both hardware integration and control software development.

The position is part of a multidisciplinary team developing a prototype DNA sequencing instrument combining microscopy, microfluidics, nanofabrication and advanced data analysis.

Initial Project

The first major task will be to design and integrate a microfluidics subsystem into our existing microscope prototype – to plan, test, order and add already commercially available components to a final prototype.

This includes selecting and integrating a commercial microfluidics system (e.g. Elveflow or similar), designing a custom sample chip holder and fluid interface, integrating control into an existing Python control software, and establishing practical operation and cleaning procedures.

The work is supported by a biochemistry team, but we are seeking for the right candidate who can make confident engineering decisions based on previous hands-on experiences connected to eg. microfluidics and laboratory automation.

Responsibilities

• Mechanically integrate new devices into a prototype life-science instrument. The initial focus is on liquid sample handling, such as flow and temperature control.

• Develop Python control and automation software, starting from existing vendor SDKs.

• Design simple mechanical parts (CAD / 3D printing)

• Hands-on prototyping and debugging in the lab

• Method development for instrument performance evaluation and self-calibration.

Over time the role will involve increasing focus on automation and device control software.

Candidate Profile

For you to enjoy performing expected activities, and being a valuable member in an ambitious and innovative team; we think you are an engineer with a strong creative mindset and with strong previous experience building/developing scientific or laboratory instrumentation.

This role suits someone who enjoys experimental prototyping in a small startup environment. The candidate should be comfortable collaborating in a multidisciplinary research environment consisting of engineering, software, biochemistry and nanofabrication experts.

Relevant backgrounds and skills include:

• Master of Science and/or Ph.D. educational background – ideally combined with a relevant Life Science focus.

• Practical experience with microfluidics systems

• Python programming for hardware control

• Comfortable with hands-on lab engineering (CAD, electronics, prototyping)

• Microscopy / Optics / Imaging

• Lab automation / Liquid handling

• Mechatronics / Robotics

A recent Ph.D. with strong hands-on instrument development experience could also be a good fit for this position.

Gnothis offer a creative environment focused on technology and product development, a competitive compensation package and plenty of room for self-development as the company expands. This is a permanent position (not consultant assignment).

If above sounds like an exciting opportunity and you would like to hear more, do not hesitate and submit your application and we will get back to you!

Gnothis AB on LinkedIn: https://www.linkedin.com/company/gnothis/posts/?feedView=all

For inquires please email us at: [email protected]