Job description

We are now looking for a Scientist to join the In vivo Bioscience team within Research and Early Development, Respiratory & Immunology in Gothenburg, Sweden.

Respiratory & Immunology is one of AstraZeneca’s main therapy areas. From a research perspective we work to understand, treat, modify and ultimately cure respiratory and autoimmune diseases. In this role, you will focus on mouse models of inflammatory bowel disease (IBD).

Key Duties and Responsibilities:

As part of the team, you will plan, execute and analyse ex vivo samples generated from in vivo studies to progress our drug discovery projects and generate publishable scientific insights. You will actively take part in scientific discussions to add valuable inputs in experimental design and data interpretation.This is a mainly lab-based role where you will be involved in ongoing projects focusing on pre-clinical experiments.

About randstad life sciences

This is a consultant assignment with Randstad Life Sciences. Randstad Life Sciences is specialized in competencies within Life Science. As a consultant with us, you get a competitive salary, benefits, and collective agreements. Your consultant manager is always there for you and ensures that you get varying and developing assignments at different companies, within different industries. At Randstad Life Sciences, your personal development is in focus, and you are offered a large network and many activities.

Deadline: 2024-04-22, selection and interviews will be ongoing. For more information: Please contact Malin Fridholm, [email protected]

Responsibilities

As part of the team, you will plan, execute and analyse ex vivo samples generated from in vivo studies to progress our drug discovery projects and generate publishable scientific insights. You will actively take part in scientific discussions to add valuable inputs in experimental design and data interpretation.This is a mainly lab-based role where you will be involved in ongoing projects focusing on pre-clinical experiments.

What you’ll do:

• As a Scientist you will be a vital member of the in vivo community and will contribute to the development and characterization of pre-clinical models of IBD to discover novel therapeutics.
• You will contribute to the analysis of in vivo studies with a specific focus on FACS analysis.

Qualifications

• At least 5 years of experience with regular FACS analysis of mouse samples (organ processing and digestion, cell staining, antibody panel set up, proficient in the use of BD FACS DIVA machines and Flowjo).
• Ability to organize, execute and interpret the results from in vivo studies according to study plans in agreement with the team leader or other colleagues.
• Experience with other in vitro methodology in addition to FACS (ELISA/MSD and/or qRT-PCR) to analyze ex vivo samples generated from in vivo studies.
• Experience of maintaining the highest standards of welfare and ethical compliance and ensuring the integrity of the generated data. Familiar with using Good Statistical Practice in animal research and applying the 3R’s (reduction, refinement and replacement) across the full range of studies.
• Valid education required for compliance to work with live animals in Sweden.
• Excellent English written and oral communication skills, including presentation skills.

Desirable for the role:

• Degree in immunology (master or PHD) and understanding of autoimmune diseases with a specific focus on gut immunology.
• Several years of hands-on experience with rodents including live animal handling, drug administration through different routes (i.v, i.p., p.o.), blood and organ sampling and processing (colon, small intestine, spleen, lymph nodes).
• Experience with animal models of inflammatory bowel disease (IBD) and in vivo PK/PD relationships.

About the company

Randstad

At Randstad, we see the possible in people. With business all over Sweden and in all areas of expertise, we help people find work that feels good, where they get the opportunity to develop and realize their true potential.

With close to 600 000 employees in 38 countries, Randstad is the global leader in the HR services industry. Our mission is to become the world’s most valued working life partner. By combining our passion for people with the power of today’s technology, we support people and organizations in realizing their true potential. We call it Human Forward.