Arbetsbeskrivning

Project assistant in biosensor development and studies on neuronal communication Project overview This project will involve the fabrication of nanomaterial modified enzyme-based biosensors for high temporal amperometric recording of glutamate and acetylcholine release at single cells during neuronal communication. The goal is to better understand neurontransmission and to study neurodegeneration. About the division The division of Chemistry and Biochemistry at the department of Chemistry and Chemical Engineering employs around 100 people, including PhD students and postdocs. The research activities at the division includes the areas of physcial chemistry, organic chemistry, nanotechnology and analytical chemistry. The research project involves the fabrication of nanostructured enzymes based electrochemical biosensors that will be used for studying neurochemical activity of glutamate and acetylcholine at single neuronal cells and for implementation to study neurodegenerative disease. Main responsibiities The candidate will be responsible for fabricating enzyme-based biosensors, characterizing the sensors and performing measurement of exocytotic acetylcholine and glutmate release activity at neuronal cells. The candidate will culture and differentiate cells into glutamatergic and cholinergic cells and perform studies related to Alzheimer´s disease. Contract terms Full-time temporary employment from 1 February 2025-30 April 2025. Qualifications The candidate should have great skills in fabrication of biosensors for detection of glutamate and acetylcholine, using carbon fiber electrodes with surface modifications using nanomaterials. In addition the candidate should have traning in ultrafast amperometric recording of single cell exocytosis activity and studies related to Alzheimer´s disease. We offer Chalmers offers a cultivating and inspiring working environment in the coastal city of Gothenburg.  Read more about working at Chalmers and our benefits for employees. Application procedure The application should be attached as PDF files, as below: CV Personal letter Other documents (optional): • Copies of completed education, grades etc. Two references that we can contact should be provided at a possible interview. Please use the button at the bottom of the page to reach the application form. We do not accept applications sent by email. Application deadline: 1 January, 2025 For questions, please contact: Professor Ann-Sofie Cans, Division of Chemistry and Biochemistry E-mail: [email protected] Phone: +46 31-7726123 *** Chalmers declines to consider all offers of further announcement publishing or other types of support for the recruiting process in connection with this position. ***   Chalmers University of Technology in Gothenburg conducts research and education in technology and natural sciences at a high international level. The university has 3100 employees and 10,000 students, and offers education in engineering, science, shipping and architecture. With scientific excellence as a basis, Chalmers promotes knowledge and technical solutions for a sustainable world. Through global commitment and entrepreneurship, we foster an innovative spirit, in close collaboration with wider society. Chalmers was founded in 1829 and has the same motto today as it did then: Avancez – forward.